Desquamation: The shedding of skin cells

January 07, 2020

Desquamation: The shedding of skin cells

Shedding of skin is a process call desquamation. In normal skin, the whole epidermis is replace in about 42 days and for the stratum corneum alone in about 14 days. That's why you should allow at least 30 days to see if the product works or not.  But if you have an immediate allergic reaction to a product, you should discontinue using it right away though.

Remember the protein bridges, desmosomes, that connect between cornecytes? Desquamation is the enzymatic process that dissolves those protein bridges and shedding of these cells. This process is opposite of the production of amino acids from proteolytic degradation of filaggrin proteins.  The proteolytic enzymes responsible for desquamation functions need the stratum corneum to be well-hydrated.  And these enzymes are located intercellularly. In the absence of water, the cells do not shed normally and the results is thick, dry, rough, and scaly skin.  There should be a balance in the production of corneocytes and shedding.  Increased production of corneocytes (as in psoriasis) or decreased shedding (as in ichthyosis) results in the accumulation of cells on the skin surface and dry, rough skin.

The skin does know how to renew itself.  It has the ability to do it.  You don't need to use strong exfoliants.  By you intervene in its nature process, if not careful you will cause more harm than good.  Over exfoliation is the cause of many skin problems.

Healthy and smooth skin can be effortlessly achieve by keeping the skin hydrated and balance and leave it alone to do what skin know best!

This is why our hydration set is loved by so many of our customers! Have you tried it yet? A must have for dry, dehydrated skin!

Source:  Handbook of Cosmetic Science and Technology




Leave a comment

Comments will be approved before showing up.


Also in Blog

Best hydrating essence for sensitive acne prone skin YOU skincare
Natural Moisturizing Factors (NMF): How our skin retains water naturally

October 11, 2019

Our stratum corneum contains free amino acids, and other nature occurring chemical lactic acid, urea, and sodium PCA, etc.  These are called “natural moisturizing factors” and are responsible for keeping the skin moist and pliable by attracting and holding water.

Continue Reading

A Quick Overview of skin anatomy and physiology
A Quick Overview of skin anatomy and physiology

July 20, 2019

Skin is the organ that protect us from the environment.  It is our widest organ with a weight of about 4 kg and 1.8 m2 surface. It prevents dehydration, stop harmful materials from penetrating into our body, helps maintain our body temperature, and act as a cushions against mechanical shock. Our skin is a living organism, therefore it goes through an aging process and under constant renewal. As we aged, its functionality also decreased.

Continue Reading

Balancing Cleansing Milk for acne prone skin
The important relationship between Cleanser, Skin pH, and Acne

July 19, 2019

If there’s one thing I can tell you that will make the biggest difference in your acne treatment or taking care of your skin …that will be choosing the right cleanser.  The right cleanser is one that won’t alter our skin pH or damage our skin barrier.

Continue Reading